South Africa will play the Black Stars of Ghana on Thursday, 14 November in Accra and welcome Sudan three days later on Sunday, 17 November at Orlando Stadium after Caf changed the initial dates for the Afcon 2021 qualifiers.
Initially, South Africa was pencilled in to play the West African country on November 15 and to host Sudan on November 19 before the continental controlling body intervened and changed the dates.
South Africa and Ghana are in Group C with Sudan and Sao Tome Principe.
Two teams from the group will qualify for Afcon 2021 in Cameroon.
Sao Tome earned a historic victory over Mauritius – winning 3-1 in the first leg of the preliminary stage and followed it up with a 2-1 victory in the second leg to complete a remarkable 5-2 aggregate win.